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As with other nsaids, anaphylactoid reactions may occur in patients without known prior exposure to ponstel.

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A blood thinner such as warfarin coumadin ; lithium eskalith, lithobid ; methotrexate rheumatrex, trexall ; diuretics water pills such as furosemide lasix ; steroids prednisone and others ; aspirin or other nsaids non-steroidal anti-inflammatory drugs such as generic etodolac lodine , flurbiprofen ansaid , indomethacin indocin , ketoprofen orudis , ketorolac toradol , mefenamic acid ponstel , meloxicam mobic , nabumetone relafen , naproxen aleve, naprosyn , and others; or an ace inhibitor such as benazepril lotensin , captopril capoten , fosinopril monopril , enalapril vasotec , lisinopril prinivil, zestril , ramipril altace , and others.

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Serious stomach ulcers or bleeding can occur with the use of ponstel.

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the mechanism of action of ponstel, like that of other nsaids, is not completely understood but involves inhibition of cyclooxygenase cox-1 and cox-2 .

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